Cytokines impact natural killer cell phenotype and functionality against glioblastoma in vitro.

Minna Sivonen, Katja A Sirviö, Sara Wojciechowski, Anssi Kailaanmäki, Satu Kaipainen, Aubrey Bailey, Martin Villalba, Tuija Kekarainen. Cytokines impact natural killer cell phenotype and functionality against glioblastoma in vitro. 2023 Sep 28:14:1227064. doi: 10.3389/fimmu.2023.1227064.

Sara Feola, Markus Haapala, Karita Peltonen, Cristian Capasso, Beatriz Martins, Gabriella Antignani, Antonio Federico, Vilja Pietiäinen, Jacopo Chiaro, Michaela Feodoroff, Salvatore Russo, Antti Rannikko, Manlio Fusciello, Satu Koskela, Jukka Partanen, Firas Hamdan, Sari M Tähkä, Erkko Ylösmäki, Dario Greco, Mikaela Grönholm, Tuija Kekarainen, Masoumeh Eshaghi, Olga L Gurvich, Seppo Ylä-Herttuala, Rui M M Branca, Janne Lehtiö, Tiina M Sikanen, Vincenzo Cerullo. PeptiCHIP: A Microfluidic Platform for Tumor Antigen Landscape Identification, doi: 10.1021/acsnano.1c04371. Epub 2021 Oct 4.

Olga L Gurvich , Katja A Puttonen, Aubrey Bailey, Anssi Kailaanmäki, Vita Skirdenko, Minna Sivonen, Sanna Pietikäinen, Nigel R Parker, Seppo Ylä-Herttuala, Tuija Kekarainen. Transcriptomics uncovers substantial variability associated with alterations in manufacturing processes of macrophage cell therapy products, 2020 Aug 20;10(1):14049. doi: 10.1038/s41598-020-70967-2.

Anniina J. Valkama, Igor Oruetxebarria, Eevi M. Lipponen, Hanna M. Leinonen, Piia Käyhty, Heidi Hynynen, Vesa Turkki, Joonas Malinen, Tuukka Miinalainen, Tommi Heikura, Nigel Parker, Seppo Ylä-Herttuala, Hanna P. Lesch. Development of large-scale downstream processing for lentiviral vectors. 2020 Mar 25; https://doi.org/10.1016/j.omtm.2020.03.025

Hanna M. Leinonen, Saana Lepola, Eevi M. Lipponen, Tommi Heikura, Tiina Koponen, Nigel Parker, Seppo Ylä-Herttuala and Hanna P. Lesch. Benchmarking of scale‐X™ bioreactor system in lentiviral and adenoviral vector production. DOI: 10.1089/hum.2019.247.

Riikka Nivajärvi, Venla Olsson, Viivi Hyppönen, Sean Bowen, Hanna M. Leinonen, Hanna P. Lesch, Jan Henrik Ardenkjær‐Larsen, Olli H.J. Gröhn, Seppo Ylä‐Herttuala, Mikko I. Kettunen. Detection of lentiviral suicide gene therapy in C6 rat glioma using hyperpolarised [1‐13C]pyruvate. 2020 Jan 07; https://doi.org/10.1002/nbm.4250

Hanna Leinonen, Eevi Lipponen, Anniina Valkama, Heidi Hynynen, Igor Oruetxebarria, Vesa Turkki, Venla Olsson, Jere Kurkipuro, Haritha Samaranayake, Ann-Marie Määttä, Nigel Parker, Seppo Ylä-Herttuala, and Hanna Lesch. Preclinical proof-of-concept, analytical development and commercial scale production of lentiviral vector in adherent cells. 2019 Aug 29; doi: https://doi.org/10.1016/j.omtm.2019.08.006.

Lesch HP. Back to the future: where are we taking lentiviral vector manufacturing. Cell and Gene Therapy Insights. 2018, Dec. 4(11):1139-1152.

Kekarainen T and Lesch HP. Welcome to the Kuopio Center for Gene and Cell Therapy. Health Europa Quarterly Issue 6. Aug 2018.

Belt H, Koponen JK, Kekarainen T, Puttonen KA, Mäkinen PI, Niskanen H, Oja J, Wirth G, Koistinaho J, Kaikkonen MU, Ylä-Herttuala S.
Temporal Dynamics of Gene Expression During Endothelial Cell Differentiation From Human iPS Cells: A
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